Find Flights from Madrid to Santiago (MAD - SCL)

Good to Know: MAD to SCL Flights

Useful information for finding cheap flights from Adolfo Suárez Madrid–Barajas to Comodoro Arturo Merino Benítez and booking your next trip

Cheapest Round Trip Flight

£1218

FRRyanair• 3 stops • 48h 34m

Sep 30 – Oct 30

The cheapest round trip flight from Adolfo Suárez Madrid–Barajas to Comodoro Arturo Merino Benítez is currently £1218

🔍 Search Flights

Cheapest Direct Flight

£1703

LALATAM Airlines• nonstop• 22h 10m

Sep 30

The cheapest nonstop flight from Adolfo Suárez Madrid–Barajas to Comodoro Arturo Merino Benítez is currently £1703

🔍 Search Flights

Fastest Flight

22h

The fastest nonstop flight from Adolfo Suárez Madrid–Barajas to Comodoro Arturo Merino Benítez takes 22h

Best Flight Deals from Madrid to Santiago

Explore the lowest round-trip fares from Madrid to Santiago. We've compared hundreds of airlines and travel sites so you don't have to.

Sep 30 - Oct 30, Economy
FR
Madrid → Santiago
48h 34m
6:20 AM - 3:25 AM • 3 stops
LA
Madrid → Santiago
27h 35m
10:00 PM - 3:00 PM • nonstop
£1218
Ryanair
Sep 30 - Oct 30, Economy
LA
Madrid → Santiago
48h 34m
12:15 AM - 9:55 PM • 2 stops
LA
Madrid → Santiago
27h 35m
10:00 PM - 3:00 PM • nonstop
£1240
LATAM Airlines
Sep 30 - Oct 30, Economy
CA
Madrid → Santiago
48h 34m
10:30 PM - 11:30 AM • 1 stop
LA
Madrid → Santiago
27h 35m
6:30 PM - 1:40 PM • 1 stop
£1518
Air China
Sep 30 - Oct 30, Economy
LA
Madrid → Santiago
44h 16m
11:59 PM - 9:55 PM • 1 stop
LA
Madrid → Santiago
21h 40m
10:00 PM - 3:00 PM • nonstop
£1720
LATAM Airlines
Sep 30 - Oct 30, Economy
LA
Madrid → Santiago
47h 10m
2:45 PM - 2:15 PM • 2 stops
LA
Madrid → Santiago
21h 40m
10:00 PM - 3:00 PM • nonstop
£1736
LATAM Airlines
Sep 30 - Oct 30, Economy
LA
Madrid → Santiago
29h 5m
11:50 AM - 12:35 AM • 1 stop
LA
Madrid → Santiago
27h 35m
4:45 PM - 1:40 PM • 1 stop
£1738
LATAM Airlines

Compare & Book Cheapest Flights from Madrid to Santiago (MAD - SCL)

Looking for a cheap last-minute deal or the best round-trip flight from Madrid to Santiago? Find the biggest savings on one-way and round-trip tickets right here.

Flights from Madrid to Santiago

Origin AirportAdolfo Suárez Madrid–Barajas , Madrid, ES
Destination AirportComodoro Arturo Merino Benítez, Santiago, CL
Distance miles

More Flight Options for Madrid (MAD) and Santiago (SCL)

Why Fareleaders for MAD to SCL Flights

Lowest Prices
Lowest Prices
Uncover the best deals on MAD to SCL flights by comparing fares from hundreds of airlines and agencies.
New Deals
New Deals Everyday
Get the best prices on MAD to SCL flights—we update our fares daily so you never miss a saving.
Best Travel Options
Best Travel Options
Compare hundreds of MAD to SCL flights and secure the best deals—we never add any service fees.
Get Fare Drop Alert
Be the first to know when fares drop for the Madrid (MAD) to Santiago (SCL)
Terms and Conditions*